5 Things About Peripheral Arterial Disease (PAD) 1: PAD May Result In Limb Loss and Death We’ll start at the end and work our way forward. PAD may result in limb loss and death. Once PAD starts becoming painful a vascular procedure or amputation are often the only things that will reduce the pain. Even opiates have been shown to poorly control pain from PAD. This is … [Read more...] about 5 Things About Peripheral Arterial Disease (PAD)